To optimize dehumidifier placement, consider structural spaces with high “Closeness” values, such as basements, attics, and crawl spaces. These areas are prone to high humidity, mold growth, and dust mites, impacting indoor air quality and health. Position the dehumidifier in well-ventilated areas with adequate air intake and exhaust to ensure proper drainage and air circulation. Consult with HVAC professionals or air quality experts to determine the optimal location and size of the dehumidifier based on the specific property and indoor air quality concerns.