Quill removal involves removing sharp, barbed quills from an animal’s body. Proper removal is crucial to prevent infection and further injury. Organizations such as the International Association for the Study of Pain and the National Institute of Health and Clinical Excellence provide guidelines. Medical professionals like physicians, surgeons, and veterinarians can assist with removal using tools like tweezers, needle-nose pliers, and gauze. Safety precautions include wearing gloves, eye protection, and seeking medical attention if necessary. Conservative methods (tweezers or pliers) and surgical removal are treatment options, with advantages and disadvantages.