Subfloor screws from Home Depot are essential for securing subfloors to joists. They are available in various lengths and diameters to suit different subfloor thicknesses and joist spacing. Subfloor screws are designed with a sharp point and a large head to provide a secure hold. The screws are self-drilling, eliminating the need for pre-drilling pilot holes. They are also coated with a corrosion-resistant finish for long-lasting durability.